Most of the establishment was working with JFK not against him. He was a liberal icon. I'm not sure there was necessarily any organized "conspiracy" against Trump. There didn't have to be. The media and DOJ were out to get him but that was mostly their radicalized ideology playing out. They knowingly perpetuated hoaxes and lies. The ends justifying any means in their opinion. They often took their cues from one another as you would see the same buzz word of the day used in every media story, but they all had TDS and were voluntarily doing everything possible to stop him. I'm not sure anyone was necessarily orchestrating this so much as they shared a common radicalized goal - to stay in power and stop Trump at all costs. That has been the driving force. It did have something similar to the effect of a psych-op operation on those most deranged with Trump hatred. No other way to explain their level of anger and hatred toward him. Those people are often unhinged. You can see many examples of that on this thread dating back to Rick Plant who posted tens of thousands of long anti-Trump rants.
They - a small group - used lawfare against Trump; abused/misused their power. That's not a "deep state". It's a part of the national security/administrative state. They didn't get together to assassinate him and then frame another person and then have future generations cover it all up. Which is a preposterous argument. Any comparison between how they tried to get Trump (they did try but they also thought he was guility) and what is alleged to have happened to JFK falls apart on the slightest examination.
I've often asked the conspiracists why they didn't use "lawfare" against JFK? That is leak damaging information about him. Supposedly the CIA controlled the media through Operation Mockingbird. So why not leak impeachable information? Instead of doing that they decided to murder him and then hope future generations would cover for them? Were they idiots?